Professor Francesco Visioli
Francesco Visioli earned a degree in Pharmacy and Pharmaceutical Chemistry from the University of Milan and a PhD in Biotechnology from the University of Brescia. Currently, he is Chief Scientist at the Madrid Institute for Advanced Studies (IMDEA)-Food. From 1996 to 2010 he was full Professor of physiopathology at the Université Pierre et Marie Curie (Paris), where he directed the “Micronutrients and cardiovascular disease” unit.
Hydroxytyrosol is a phenylethanoid,
a type of phenolic phytochemical with antioxidant properties.
Olive oil is the principal source of fat in the Mediterranean diet, which has been associated with a lower incidence of coronary heart disease and certain cancers. Though unknown to most consumers, there are two major categories of olive oil: “olive oil” and “extra virgin olive oil”. The former is, in fact, a mixture of extra virgin and refined olive oils, which is oil whose acidity at production exceeded legal limits.As opposed to olive oil, extra virgin olive oil contains appreciable quantities of phenolic compounds. The absolute amounts and relative proportions depend on several factors such as cultivar, production methods, storage, etc. Notably, phenolic compounds in extra-virgin olive oil are responsible for its peculiar pungent taste and for its high stability. Among the various olive phenols, hydroxytyrosol (2,4 dihydroxyphenyl ethanol) is attracting much attention due its interesting pharmacological activities. Research in this field initiated in the early ‘90s, when pure hydroxytyrosol became available by HPLC isolation from extra virgin olive oil.
Breast cancer is a form of cancer that affects the cells of the breast. It is a type of cancer originating from breast tissue, most commonly from the inner lining of milk ducts or the lobules that supply the ducts with milk and it is a disease in which certain cells in the breast become abnormal and multiply without control or order to form a tumor.
Colorectal cancer, commonly known as colon cancer or bowel cancer, is a cancer from uncontrolled cell growth in the colon or rectum (parts of the large intestine), or in the appendix. Genetic analysis shows that colon and rectal tumours are essentially genetically the same cancer.
Prostate cancer is a form of cancer that develops in the prostate, a gland in the male reproductive system. Most prostate cancers are slow growing. However, there are cases of aggressive prostate cancers. The cancer cells may metastasize (spread) from the prostate to other parts of the body, particularly the bones and lymph nodes.